5 doctors weighed in:

What are the chances of having consecutive children with down's?

5 doctors weighed in
Dr. James Ferguson
Pediatrics
3 doctors agree

In brief: Depends on pattern

This would be rare for classical trisomy 21 but could be very high for a translation 21.
I favor testing all ds infants for their chromasome pattern. If a translocation pattern is found, the parents need chromasome studies to see if one is a balanced carrier. ( ballanced 21 carriers are unaffected and have a piece of a 21 stuck on another chromasome/ but in total have all they need & no extra.

In brief: Depends on pattern

This would be rare for classical trisomy 21 but could be very high for a translation 21.
I favor testing all ds infants for their chromasome pattern. If a translocation pattern is found, the parents need chromasome studies to see if one is a balanced carrier. ( ballanced 21 carriers are unaffected and have a piece of a 21 stuck on another chromasome/ but in total have all they need & no extra.
Dr. James Ferguson
Dr. James Ferguson
Thank
Dr. Padmavati Garvey
Obstetrics & Gynecology

In brief: < 1 %

This would be extremely rare even at an advanced maternal age.
If it did happen you and your partner would need to have your chromosomes checked.

In brief: < 1 %

This would be extremely rare even at an advanced maternal age.
If it did happen you and your partner would need to have your chromosomes checked.
Dr. Padmavati Garvey
Dr. Padmavati Garvey
Thank
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