Are extreme pain and numbness normal after a demerol (meperidine hydrochloride) shot?

Not typically. Where did you have the shot and where is your pain. Local pain at the site of the injection is not uncommon and should be self limiting. Where is your numbness. In the typical site of im injections it would be unlikely to hit a nerve and cause pain and numbness. If you got the injection intravenously, the IV insertion could cause localized pain and nerve trauma leading to pain and numbness.

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What are the side effects of demerol (meperidine hydrochloride) use, abuse?

Many. Opioids cause sedation, nausea, itchiness, constipation, respiratory depression, and death in large doses when not tolerant. Meperidine is unique in that its metabolite, normeperidine, can accumulate and cause neuroexcitation and seizures, especially in patients with kidney problems. Read more...