What is the difference between open heart surgery and by-pass surgery?

Not much. Open heart surgery is any surgery in which the chest cavity /sternum is opened. It doesn't necessarily mean bypass surgery is performed. Bypass surgery is a type of open heart in which blockages are bypassed with conduits that are arterial or veinous.

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Can you please tell me how open heart surgery and bye pass surgery differ?

Overlap. Coronary artery bypass operations are heart operations done for atherosclerosis with obstruction to blood flow and symptoms of angina or heart attack. Heart surgery includes coronary, congenital, valves, tumors, etc. Truly open heart surgery is inside the heart, and coronary is on the surface, but the terminology has become commonplace. Read more...