3 doctors weighed in:
Is methrotrexate a causative factor for pulmonary fibrosis?
3 doctors weighed in

Dr. Aaron Milstone
Internal Medicine - Pulmonology
1 doctor agrees
In brief: Yes
Rarely Methotrexate can cause fibrosis of the lungs.
An inflammation (called pneumonitis) is more common. Lung function should be checked at least yearly while on this drug.

In brief: Yes
Rarely Methotrexate can cause fibrosis of the lungs.
An inflammation (called pneumonitis) is more common. Lung function should be checked at least yearly while on this drug.
Dr. Aaron Milstone
Dr. Aaron Milstone
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Dr. Craig Brown
Internal Medicine - Pulmonology
In brief: Methotrexate
One very well known side effect of methotrexate(mtx) is increased inflammation in the lung.
It looks like fibrosis on a ct scan. Once mtx is discontinued, symptoms and imaging typically improve within 4-6 weeks. Less frequently, mtx lung is irreversible.

In brief: Methotrexate
One very well known side effect of methotrexate(mtx) is increased inflammation in the lung.
It looks like fibrosis on a ct scan. Once mtx is discontinued, symptoms and imaging typically improve within 4-6 weeks. Less frequently, mtx lung is irreversible.
Dr. Craig Brown
Dr. Craig Brown
Thank
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