5 doctors weighed in:
How can the cystic fibrosis gene affect tuberculosis?
5 doctors weighed in

David Escobar
Family Medicine
3 doctors agree
In brief: Lung Function
The gene itself will not affect tuberculosis.
However, if an individual receives 2 recessive genes of the cftr mutation from their parents, they will develop cystic fibrosis (cf). Because CF can lead to repeated bacterial lung infections (among other things), the lungs would already be in a weakened state if exposed to the causative agent of tuberculosis. This might lead to faster disease onset.

In brief: Lung Function
The gene itself will not affect tuberculosis.
However, if an individual receives 2 recessive genes of the cftr mutation from their parents, they will develop cystic fibrosis (cf). Because CF can lead to repeated bacterial lung infections (among other things), the lungs would already be in a weakened state if exposed to the causative agent of tuberculosis. This might lead to faster disease onset.
David Escobar
David Escobar
Answer assisted by David Escobar, Medical Student
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Dr. Klaus d Lessnau
Internal Medicine - Pulmonary Critical Care
In brief: No connection
Why would you ever ask?

In brief: No connection
Why would you ever ask?
Dr. Klaus d Lessnau
Dr. Klaus d Lessnau
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