2 doctors weighed in:

Is a neural tube defect a chromosomal mutation or a gene mutation?

2 doctors weighed in
Dr. Richard Tholen
Surgery - Plastics
1 doctor agrees

In brief: Both or neither.

While neural tube disorders can be a genetic mutation (gene is a functional unit of heredity occupying a specific spot--locus--on a chromosome), they occur most commonly in the setting of Folic Acid deficiency during pregnancy--hence prenatal vitamins with folic acid.
Ntds occur in 1/1000 births, and range from spina bifida occulta to anencephaly.

In brief: Both or neither.

While neural tube disorders can be a genetic mutation (gene is a functional unit of heredity occupying a specific spot--locus--on a chromosome), they occur most commonly in the setting of Folic Acid deficiency during pregnancy--hence prenatal vitamins with folic acid.
Ntds occur in 1/1000 births, and range from spina bifida occulta to anencephaly.
Dr. Richard Tholen
Dr. Richard Tholen
Thank
Get help from a real doctor now
Dr. Adam Levy
Board Certified, Obstetrics & Gynecology
34 years in practice
1M people helped
Continue
111,000 doctors available
Read more answers from doctors