Can you safely take hydrocodone/acetaminophen with naproxen?

Yes. There is no problem mixing them as long as you take them as prescribed and have no underlying contraindications to them.

Related Questions

I took 2 hydrocodone-acetaminophen 10/500 can I take naproxen 500 mg too?

Yes. I often add an NSAID to opioid medications for acute pain. They work differently to decrease pain and inflammation. Read more...