11 doctors weighed in:
Can cystic fibrosis affect both respiratory and digestive system?
11 doctors weighed in

Rishi Kumar
Anesthesiology
8 doctors agree
In brief: Absolutely
The thicker mucous secretions inherent to cystic fibrosis (CF) can cause a relative obstruction in clearing the airway tree of particulate matter/germs.
Similarly, these secretions can obstruct the passage of pancreatic enzymes into the intestine leading to mal-digestion.

In brief: Absolutely
The thicker mucous secretions inherent to cystic fibrosis (CF) can cause a relative obstruction in clearing the airway tree of particulate matter/germs.
Similarly, these secretions can obstruct the passage of pancreatic enzymes into the intestine leading to mal-digestion.
Rishi Kumar
Rishi Kumar
Answer assisted by Rishi Kumar, Medical Student
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1 comment
Dr. William Walsh
The initial presentation of cystic fibrosis used to be the gastrointestinal system.
Dr. William Walsh
Addiction Medicine
3 doctors agree
In brief: Yes
It generally does affect both the mucus in the airways, the pancreas, and the gut.
Chronic airway infection leading to lung failure, pancreatic problems leading to pancreatic insufficiency, and chronic constipation are very common problems in patients with cf. Treatment mitigates (but does not eliminate) the consequences of the disease for most, although for c. 5% a direct treatment exists.

In brief: Yes
It generally does affect both the mucus in the airways, the pancreas, and the gut.
Chronic airway infection leading to lung failure, pancreatic problems leading to pancreatic insufficiency, and chronic constipation are very common problems in patients with cf. Treatment mitigates (but does not eliminate) the consequences of the disease for most, although for c. 5% a direct treatment exists.
Dr. William Walsh
Dr. William Walsh
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