What are the long term affects of lack of oxygen to legs in emphysema?

Bad. Lack of oxygen in emphysema is general and not localized to one part of the body. Most critical and sensitive parts are brain and heart. If there is additional poor circulation to the legs, lack of oxygen will contribute to leg cramps, leg pain, nerve damage, poor wound healing and gangrene.

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Could you tell me what are long term affects of lack of oxygen to legs in emphysema?

Oxygen delivery. Lack of oxygen to any part of the body from any cause may cause ischemia. This causes the cells to do their work via alternate pathways. This causes Lactic Acid buildup pain and eventually cell death. Claudication is a term you may have heard when there is poor circulation to the legs causing pain. The poor circulation reduces the amount of oxygen delivered. Read more...