2 doctors weighed in:

Can I take promethazine codeine syrup with benadryl (diphenhydramine)?

2 doctors weighed in
Dr. James Marx
Pain Management
1 doctor agrees

In brief: Why?

Promethazine and Benadryl (diphenhydramine) are both antihistamines.
The combination of prometh. With Codeine should be used the treatment of uncontrolled coughing. Unfortunately, the purple syrup is frequently abused in a number of unusual ways. To add Benadryl (diphenhydramine) to the combination syrup doesn't make much sense in most circumstances and could lead to at least drowsiness or worse.

In brief: Why?

Promethazine and Benadryl (diphenhydramine) are both antihistamines.
The combination of prometh. With Codeine should be used the treatment of uncontrolled coughing. Unfortunately, the purple syrup is frequently abused in a number of unusual ways. To add Benadryl (diphenhydramine) to the combination syrup doesn't make much sense in most circumstances and could lead to at least drowsiness or worse.
Dr. James Marx
Dr. James Marx
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