Can I continue to be an effective nurse with a kidney disease?

Yes, unless severe. Stages 4 and 5 of chronic kidney disease will be associated with fatigue and feeling poorly that will interfere with work. However, better stages will still be compatible with being able to work ok. Need to note that difference between stage 3 and 4 may be only the difference between 29 & 31 "%" of kidney function and other associated illnesses will also modify the above conclusion.