How long does it take for the Depo-Provera shot to be active?

Its fast. If you are referring the the birth control shot, it is considered protective in 24 hours. However, the first shot should be given when you are on your period. So pregnancy risk should be nearly zero at that time. For more info go to: http://www.Acog.Org/~/media/for%20patients/faq159.Pdf?Dmc=1&ts=20120922t1830582752.
About one week. One week if given after 5 days of the menstrual cycle. If given during the first 5 days of the mesntrual cycle then it works immediately. Would still recommend protection for about 1 week.

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How long does it take for the Depo-Provera shot to get out of your system?

Depends. Depo Provera (medroxyprogesterone) is used for birth control. It can be administered im or sq. The half life of an im injection is 50-55 days, a bit longer for sq. This means the medication will remain in your system 250-275 days.(5x the 1/2 life). Read more...

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In . In the average woman the depo shot lasts for 12 weeks. Every woman is different however as far as when they will start ovulating again after the depo wears off. Read more...

How long is it supposed to it take for the Depo-Provera shot to get out of ur system?

Up to 6 months. It can take as long as 6 months for a woman's cycle to return to normal after depot provera (medroxyprogesterone). Granted, that's not most women, but for some women that is the case. Most women are having regular cycles within 1-2 months after 12 week (3 month) window of shot. Read more...