My girlfriend has one, white vaginal spot and has little white discharge. It causes some irritation but it does not burn while she urinates?

Needs testing. One vaginal white spot concerns me. Herpes and syphilis can often present as "one little spot." please schedule a visit for std testing. Hopefully this is nothing but better safe than sorry.
Vaginal Discharge. The things to be worried about include if the discharge has a yellow or green color, is clumpy like cottage cheese, or has a bad odor. If worried, see a doctor.