What occurs after a bone marrow transplant is needed for chronic myeloid leukemia?
9 doctors weighed in:
What occurs after a bone marrow transplant is needed for chronic myeloid leukemia?
9 doctors weighed in
Dr. Stephen Noga
Internal Medicine - Oncology
In brief:
Hopefully cure
CML is a major success story.
About 30 years ago up until about 2000, the standard for cure was allogeneic bone marrow transplantation. Now, new drugs can achieve long term remissions of a decade or more. This is the new standard of care but despite this, when these drugs fail, bone marrow transplant is still the gold standard and still the only curative therapy. There are many complications.
In brief:
Hopefully cure
CML is a major success story.
About 30 years ago up until about 2000, the standard for cure was allogeneic bone marrow transplantation. Now, new drugs can achieve long term remissions of a decade or more. This is the new standard of care but despite this, when these drugs fail, bone marrow transplant is still the gold standard and still the only curative therapy. There are many complications.
Dr. Stephen Noga
Thank
Dr. Ritesh Rathore
Internal Medicine - Hematology & Oncology
In brief:
Long process
The first critical steps are donor finalization, transplant chemo followed by stem cell transplant.
After this, recovery starts and first 100 days are important for infections, marrow recovery, potential graft vs host disease, and other complications. Gradually, immunesuppressive meds and then antibiotics are withdrawn. Booster vaccines are done from 12 mths onwards and follow up is for 5 yrs.
In brief:
Long process
The first critical steps are donor finalization, transplant chemo followed by stem cell transplant.
After this, recovery starts and first 100 days are important for infections, marrow recovery, potential graft vs host disease, and other complications. Gradually, immunesuppressive meds and then antibiotics are withdrawn. Booster vaccines are done from 12 mths onwards and follow up is for 5 yrs.
Dr. Ritesh Rathore
Thank
Dr. David Rizzieri
Internal Medicine - Hematology & Oncology
In brief:
Long recovery period
Depending on your condition, your donor match etc, you will likely be seen daily for a few months at the transplant center for close care, watching for infections, guarding against transplant effects, ensuring nutrition and exerecise improve.
The ibmtr website and lls websites have good patient information available for this.
In brief:
Long recovery period
Depending on your condition, your donor match etc, you will likely be seen daily for a few months at the transplant center for close care, watching for infections, guarding against transplant effects, ensuring nutrition and exerecise improve.
Thank
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