4 doctors weighed in:
What is the difference between a needle directed biopsy and a sentinel node biopsy?
4 doctors weighed in

Dr. Devon Webster
Internal Medicine - Oncology
2 doctors agree
In brief: Size
A needle-directed biopsy means a hollow needle is stuck into a tumor or lymph node, and only the amount of tissue that fits inside the needle is removed.
A sentinel node biopsy removes several lymph nodes entirely and the entire lymph node is examined under the microscope. A sentinel node biopsy requires an injection ahead of time to see which nodes are first in the chain of lymph nodes.

In brief: Size
A needle-directed biopsy means a hollow needle is stuck into a tumor or lymph node, and only the amount of tissue that fits inside the needle is removed.
A sentinel node biopsy removes several lymph nodes entirely and the entire lymph node is examined under the microscope. A sentinel node biopsy requires an injection ahead of time to see which nodes are first in the chain of lymph nodes.
Dr. Devon Webster
Dr. Devon Webster
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Dr. Sean Canale
Breast Surgery
In brief: Diagnos vs staging
A "needle directed biopsy" is likely being used to establish a diagnosis (benign or malignant).
A sentinel node biopsy is part of the pathologic staging process once a malignant diagnosis has already been established.

In brief: Diagnos vs staging
A "needle directed biopsy" is likely being used to establish a diagnosis (benign or malignant).
A sentinel node biopsy is part of the pathologic staging process once a malignant diagnosis has already been established.
Dr. Sean Canale
Dr. Sean Canale
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Dr. Barry Rosen
Surgery
In brief: Anesthesia
A needle biopsy is performed when we have found an abnormality and want to determine whether it is cancerous or not; it is performed under local anesthesia in a doctor's office or breast center. A sentinel node biopsy is a surgical procedure to determine if a cancer has 'spread' to the lymph nodes; this information is used to stage the cancer, to guide subsequent therapy.

In brief: Anesthesia
A needle biopsy is performed when we have found an abnormality and want to determine whether it is cancerous or not; it is performed under local anesthesia in a doctor's office or breast center. A sentinel node biopsy is a surgical procedure to determine if a cancer has 'spread' to the lymph nodes; this information is used to stage the cancer, to guide subsequent therapy.
Dr. Barry Rosen
Dr. Barry Rosen
Thank
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