5 doctors weighed in:

What is the difference between a complete and a partial hydatidiform mole?

5 doctors weighed in
Brittany Chan
Pediatrics
3 doctors agree

In brief: Genetics + more

A complete mole is formed when a sperm fertilizes an empty egg & duplicates, or when two sperm fertilize an empty egg.
It has 46 chromosomes(all paternal). A partial mole develops when two sperm(or one sperm that duplicates) fertilize an egg & has 69 chromosomes. Fetal parts are usually only found in partial moles. Complete moles inc risk for choriocarcinoma(a type of tumor) more than partial moles.

In brief: Genetics + more

A complete mole is formed when a sperm fertilizes an empty egg & duplicates, or when two sperm fertilize an empty egg.
It has 46 chromosomes(all paternal). A partial mole develops when two sperm(or one sperm that duplicates) fertilize an egg & has 69 chromosomes. Fetal parts are usually only found in partial moles. Complete moles inc risk for choriocarcinoma(a type of tumor) more than partial moles.
Brittany Chan
Brittany Chan
Answer assisted by Brittany Chan, Medical Student
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Dr. John Geisler
Gynecology - Oncology

In brief: Molar pregnancy

A partial mole develops at either at conception (2 sperm fertilize 1 egg) or immediately after conception (1 sperm enters an egg and duplicates).
A complete mole forms similarly but with an empty egg. A partial mole has about a 5% and a complete mole 15% chance of becoming a gestational trophoblastic neoplasia.

In brief: Molar pregnancy

A partial mole develops at either at conception (2 sperm fertilize 1 egg) or immediately after conception (1 sperm enters an egg and duplicates).
A complete mole forms similarly but with an empty egg. A partial mole has about a 5% and a complete mole 15% chance of becoming a gestational trophoblastic neoplasia.
Dr. John Geisler
Dr. John Geisler
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