What is a autologous bone marrow transplant?

The patient is donor. In case of myeloma certain lymphomas in general patients receive chemotherapy , achieve a response and then have stem cells mobilized from their marrow- frozen- patient goes through high doses of chemo to clear the marrow or kill as many tumor cells as possible and then reinfuse cells back. The idea is that high doses of chemotherapy can cause prolong remission or cure.
Stem cell transplant. An autologous bone marrow or stem cell transplant involves giving a patient high doses of chemotherapy followed by infusion of their own bone marrow or blood stem cells. It is a treatment generally used to treat certain blood cancers. Rarely it is used for certain solid tumors. There are clinical trials evaluating the role of these transplants for certain autoimmune disorders too.
Autologous transpant. When patient own cells are infused back to patient.

Related Questions

What is an autologous bone marrow transplant and when is it used?

5 kind of Bone M T. Autologous transplant—transplanted cells come from the body of the transplant recipient. Allogeneic transplant—transplanted cells come from a donor who may be related to the recipient (a family member) or unrelated. The advantage to using the child’s own stem cells is that he or she will not face the complications of graft-versus-host disease. However, with an autologous transplant the child does. Read more...
High dose chemo. This is a treatment that uses very high doses of chemotherapy and/or radiation to treat cancers. The doses are so high that the normal bone marrow is destroyed. The patient's own bone marrow or stem cells are then reinfused to allow the bone marrow to recover. It is used for certain cancers and some autoimmune diseases. Read more...

How long does the autologous bone marrow transplantation take?

About 4-6 weeks. There are 2 steps- the first is to collect your stem cells which usually is a 5-15 day process. Then the next step is the transplant phase which usually involves about a week of therapy, then getting your own saved cells thawed and infused back to you like a blood transfusion (over an hour for instance), then 2-4 weeks of recovery. Read more...

How dangerous is it to get a bone marrow transplant?

Risky Business. Bone marrow transplantation (or stem cell transplantation) carries a less than 5% chance of mortality from complications when done in the autologous (self) setting. Allogeneic (from another donor) bmt however is riskier with about a mortality rate of 10-20% using related donors and up to 30% using unrelated donors because of graft-versus-host disease. Read more...
Definitely has risks. While techniques are improving for allogeneic transplant, and the procedure can now be done in older patients, there is a significant risk of chronic illnes or death. To choose to have a transplant, a patient must have a life threatening condition where the risk of not having a transplant significantly outweighs the dangers of the procedure. Autologous transplant, if appropriate, is much safer. Read more...

What are complications post- bone marrow transplant?

Many! Risks are lower if you had your own cells (autologous) or a twin's cells (syngeneic), and higher if you had someone else's (allogeneic). There are short-term and long-term risks. Risks include graft vs host disease, infections (some fatal), liver problems, bleeding, cataracts, infertility, heart damage, lung damage, kidney damage, and others. Read more...