A minority is. Pancreatic adenocarcinoma, arising from ducts/epithelial tissue, is mainly "sporadic", but can run in families. Pancreatic cancer has also been related to brca mutation, fammm syndrome, and some other inherited conditions. The familial pancreatic cancer registry is at johns hopkins. A minority of neuroendocrine tumors of the pancreas are associated with multiple endocrine neoplasia (men) syndromes.
Not usually. But a particular form, which is part of a genetic syndrome (men i) is genetic.
The important loci. Brca2, palb2, cdkn2a (a melanoma / pancreatic cancer locus), mutant trypsinogen (thankfully rare but the strongest link), lynch hereditary nonpolyposis coli loci, and peutz-jegher's are the best-known genetic loci. Others may await discovery. Whether it is worth being tested for these, and what you would do with the information, is a call to be made by you and your physician. Read more...