7 doctors weighed in:

Can Prozac (fluoxetine) cause manic depression?

7 doctors weighed in
Dr. Jonathan Nehrer
Pediatrics - Psychiatry
4 doctors agree

In brief: Maybe

Prozac (fluoxetine) is an antidepressant.
Many antidepresants including Prozac (fluoxetine) can cause patients who have bipolar disorder or who are prone to symptoms of bipolar, to develop bipolar symptoms. The best way to avoid this is to work with a psychiatrist who can provide meds for both the depressive and the manic symptoms of bipolar moods.

In brief: Maybe

Prozac (fluoxetine) is an antidepressant.
Many antidepresants including Prozac (fluoxetine) can cause patients who have bipolar disorder or who are prone to symptoms of bipolar, to develop bipolar symptoms. The best way to avoid this is to work with a psychiatrist who can provide meds for both the depressive and the manic symptoms of bipolar moods.
Dr. Jonathan Nehrer
Dr. Jonathan Nehrer
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Dr. Alan Ali
Psychiatry
1 doctor agrees

In brief: Prozac (fluoxetine)

Prozac (fluoxetine) does not cause manic depression, but can trigger manic episodes in bipolar patients.

In brief: Prozac (fluoxetine)

Prozac (fluoxetine) does not cause manic depression, but can trigger manic episodes in bipolar patients.
Dr. Alan Ali
Dr. Alan Ali
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Dr. Kira Stein
Psychiatry
1 doctor agrees

In brief: Sometimes

To treat bipolar depression, antidepressants like Prozac (fluoxetine) can sometimes be added to mood stabilizing agents, but since they can trigger a switch to mania, patients need to be closely monitored.

In brief: Sometimes

To treat bipolar depression, antidepressants like Prozac (fluoxetine) can sometimes be added to mood stabilizing agents, but since they can trigger a switch to mania, patients need to be closely monitored.
Dr. Kira Stein
Dr. Kira Stein
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Dr. Andrew Berry
Clinical Psychology

In brief: Likely not

I have never heard of Prozac (fluoxetine) causing mania or depression in anyone who suffers from manic depression.
Manic depression is medicated by mood stabilizers such as lithium or depakote, and not Prozac (fluoxetine) which is typically used for depression alone, and not mania.

In brief: Likely not

I have never heard of Prozac (fluoxetine) causing mania or depression in anyone who suffers from manic depression.
Manic depression is medicated by mood stabilizers such as lithium or depakote, and not Prozac (fluoxetine) which is typically used for depression alone, and not mania.
Dr. Andrew Berry
Dr. Andrew Berry
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