Yes, very rare
Basal cell carcinoma
is locally invasive, aggressive, and destructive effects of this tumor on skin and surrounding thus usually diagnosed and treated early.
, it is very rare to see a metastatic bcc. Estimates of the metastatic bcc have ranged from 0.0029 to 0.55 %. It can spread to the lung, bone, liver. An oral hedgehog pathway inhibitor , vismodegib, is recently approved to treat metastatic bcc.