Does spironolactone block testosterone?

Not really. Spironolactone is an old, commonly used (but not really effective) diuretic that has an interesting side effect: its chemical structure is similar enough to block testosterone receptors in the face and scalp, and helps to decrease acne, oily skin, and facial hair growth.

Related Questions

Does spironolactone actually increase basal levels of estrogen or does it just block androgens, decreasing testosterone?

Spironolactone. 26F NY asks: Does spironolactone actually increase basal levels of estrogen or does it just block androgens, decreasing testosterone? ANS: complex: decrease T production by testis, increases T conversion to E2 so more estrogen and displaces T from SHBG. Binds with T receptors thus acting like anti T. I specialize in BP and diet and drug RX. Happy to do 2nd opinion. Read more...

Anything else besides Spironolactone, Finasteride, Metformin & bcps that help acne & block testosterone from PCOS? Do work but can't tolerate them.

Many meds. In my opinion there are too many meds on the list. Please discus this with your primary doctor. If she/he continues with the number of meds you mention, please see someone with a bit mores sense. Not surprised you can't tolerate medical items. Please keep me informed. Read more...