4 doctors weighed in:

How exactly does herceptin (trastuzumab) work?

4 doctors weighed in
2 doctors agree

In brief: Blocks cell growth

It is a protein that binds to receptors on breast cancer cells called her-2. Her-2 causes breast cancer cells to grow uncontrollably. When Herceptin (trastuzumab) binds to these cells, it slows their growth. However, not all breast cancer cells contain the her-2 receptors. Patients must be tested for the presence of her-2 receptors before they are started on herceptin (trastuzumab).

In brief: Blocks cell growth

It is a protein that binds to receptors on breast cancer cells called her-2. Her-2 causes breast cancer cells to grow uncontrollably. When Herceptin (trastuzumab) binds to these cells, it slows their growth. However, not all breast cancer cells contain the her-2 receptors. Patients must be tested for the presence of her-2 receptors before they are started on herceptin (trastuzumab).
Dr. Michael Zadeh
Dr. Michael Zadeh
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Dr. Devon Webster
Internal Medicine - Oncology

In brief: Binds to tumor

Herceptin (trastuzumab) is a man-made antibody that binds to cancer cells if they express the her2 receptor. It acts like "seasoning" for the immune system, attracting immune cells which kill the tumor cells.
That's a simplistic explanation, because no one really understands what happens when Herceptin (trastuzumab) binds to tumor cells. There are many theories, but we know immune cells are necessary for it to work.

In brief: Binds to tumor

Herceptin (trastuzumab) is a man-made antibody that binds to cancer cells if they express the her2 receptor. It acts like "seasoning" for the immune system, attracting immune cells which kill the tumor cells.
That's a simplistic explanation, because no one really understands what happens when Herceptin (trastuzumab) binds to tumor cells. There are many theories, but we know immune cells are necessary for it to work.
Dr. Devon Webster
Dr. Devon Webster
Thank
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