Can caregiver stress affect my wife's health?

Caregiver Stress. Yes, caregiver stress can affect health. Caregivers are more likely to have symptoms of depression & anxiety; have higher levels of stress hormones; are more likely to have long-term medical problems such as heart disease, cancer, diabetes, or arthritis; have weaker immune responses to the flu vaccine; have slower wound healing, etc. While caregivers do care, the process can be a health risk.