What is the difference between anti-estrogens and anti-aromatases for breast cancer?

"cousin-drugs" Tamoxifen ("anti-estrogen") and aromatase inhibitors (ai) are both used for treating breast cancers that are estrogen-receptor +. Ai's are only suitable after menopause but may be slightly more effective; furthermore, they are not associated with any increased risk of uterine cancer like tamoxifen.
Pharmacology. Anti-estrogens block the receptors to which estrogen attaches on the cell. Anti-aromatases prevent estrogen from being made in the body.

Related Questions

Why do we give anti-estrogen drugs to post-menopausal women with breast cancer?

Anti-estrogen drugs. Anti-estrogen drugs are given to both premenopausal and postmenopausal women whose cancer is estrogen receptor-positive or progesterone receptor-positive. These cancer may grow when exposed to estrogen. Anti-estrogen medications block or reduce estrogen that is normally produced by the ovaries in premenopausal women or by fat cells, liver, adrenal glands or other organs in postmenopausal women.

How do breast cancer anti estrogen pills work?

Starve tumor. Many tumors are fed by estrogen - the main female horomone. Anti-estrogen pills block the effects of estrogen (in a variety of different ways) and thereby starve the tumor from a vital growth factor. Even if you are postmenopausal (or even male) your body still produces estrogen in places like the adrenals and subcutaneous fat.
Aromatase inhibitor. An aromatase inhibitor blocks the conversion of testosterone like hormones in fat cells to the strong estrogen (estrone).

What is estrogen receptor positive breast cancer?

Estrogen-SensitiveCA. Normal breast cells have estrogen receptors which are like locks that estrogen "keys" fit into. Many breast cancer cells also have these estrogen receptors, which is good for 2 reasons: (1)these cancers tend to be less aggressive (since they resemble normal breast cells), and; (2)"anti-estrogens" such as tamoxifen can be very effective chemotherapeutic agents for these cancers.
One with receptors. These are tumors with estrogen receptors on them. This makes them susceptable to some chemotherapeutic agents, like tamoxifen.

What is meant by having estrogen receptor positive breast cancer?

Hormone responsive. Er positive breast cancer means that the cancer expresses estrogen receptors. This is beneficial because we can hormonally manipulate this type of cancer with drugs like tamoxifen and Arimidex (anastrozole) which are antiestrogens.
ER+. Estrogen receptors are small proteins found on the surface of some cancer cells. A positive result means the proteins are present, a negative result means they are not present.
Feeds the cancer. Most breast cancers are estrogen receptor positive. The cancer cells have receptors that fit the estrogen molecule that a body produces. Think: a lock and key - when estrogen binds to the receptor the tumor cell is stimulated to grow and divide. Er+ tumors can be blocked by tamoxifen and Arimidex (anastrozole) (and others) that interfere with this pathway.

Is boron a synthetic estrogen? And is it to be avoided if you have had estrogen positive breast cancer, but suffer from osteoporosis?

Boron. I have not heard about boron being a synthetic estrogen. It can theoretically cause thyroid issues because it can displace iodine which is important in building the thyroid hormone.
Common. A cysts is simply a fluid filled structure within the ovary usually from ovulation. There are many different types of cysts, most being benign. Most will come and go on their own;however, a few will grow large and cause symptoms.
Yes. Multiple other available treatment for osteoporosis including biphosphonates, calcitonin and teriparatide. Also include resistance excercise and it d supplement if indicated.