What are the non-genetic causes of breast cancer for the women?

Our Environment. Most cases of breast cancer in the US are unrelated to genetics and are believed to be due to our environment. Breast cancer is a disease of the modern world and is much less common in developing nations. Whether it is a byproduct of what we breathe and/or what we eat, the exact causes are unclear. However, we do see cancer more commonly in women with early menarche, late menopause, etc.
Multifactorial. The majority of women who develop breast cancer have no family history of breast cancer. Risk factors include estrogen therapy, obesity, early menarche, late menopause, and sometimes just plain bad luck.

Related Questions

Is breast cancer genetic or caused by the environment or both?

Both. Only 10-20% of breast cancers are genetically related. We are not sure what causes the remainder, but environmental factors (such as the organochloride pesticides that were sprayed 30-50 years ago) are potentially responsible. Estrogen replacement is contributing to some, and the fact that women are living to be older with each generation increases the number of elderly breast cancer. Read more...
Yes. App. 10-15% of all breast cancers are believed to be related to hereditary risks; therefore, in a sense, the other 85-90% are related to "environmental" factors. Unfortunately, we don't know what specific triggers are responsible for breast cancer development; but, we do know that breast cancer occurs much more frequently in developed countries. This, regrettably, is a disease of modern life. Read more...

What type of genetic mutation causes breast cancer?

Many. If you inherit mutated brca1 or brca2 from a parent, your odds are greatly increased. All cancers arise from accumulated mutations and natural selection over your own lifetime, but these can actually be passed from parent to child. Read more...

Which type of genetic mutation can cause breast cancer?

BRCA. The most commonly described genetic mutations associated with family history include brca1 and brca2 gene mutations. There are several other familial cancer syndromes though, and can be related to other genes such as p53 (li fraumeni syndrome) and pten (cowden's disease). Hereditary genetic syndromes as a whole are rare and comprise only about 10% of patients who have breast cancer. Read more...

What is the genetic recurrence of breast cancer?

10-15% Hereditary. We believe that only 10-15% of breast cancers are hereditary, with the rest being environmental in origin. People w/the hereditary form of breast cancer tend to get diagnosed earlier in life and may get cancer in both breasts. When treated by lumpectomy or (single) mastectomy, it is not uncommon to develop a second, unrelated breast cancer; therefore, many opt for double mastectomies. Read more...

I need your expertise, is breast cancer genetic?

Genetics can play a. Significant role for some women (not for others). Include: being female, increasing age, genetics, family history of breast cancer, previous breast cancer, being caucasian, dense breast tissue, some previous benign breast conditions, never having given birth or 1st child after age 30, early menarche, late menopause, radiation (chest), exposure to diethylstilbestrol, hormone replacement after >>. Read more...

What is the benefit of getting genetic breast cancer testing?

Knowledge is Power. The brca test is a simple (tho, very expensive) blood test to determine if one carries the risk of developing the hereditary form of breast (& ovarian) cancer. Affected people have a 50%chance of passing this on to their children. If the test is (-), this can be very reassuring; if (+), one may choose to be proactive and undergo prophylactic (preventive) mastectomies and oophorectomies. Read more...
Genetic Testing . About 5 % of breast cancer patients may have brca 1 or brca 2. It is very important for patients who are positive for brca 1 or 2 who will be recommended to have resection of both breast and her ovarian also about 25% of breast cancer patients may have her 2 neu. Cellular receptor is human epidermal growth factor receptor 2 (her2/neu); its presence correlates with a poorer prognosis. The excellent. Read more...
For patient & family. It will be useful for both patient and her children if a patient with breast cancer is + for brca 1/2 mutation- she also has sgnificant risk to develop ovarian cancer so prophylactic surgery would be recommended. Other consequences for the family- the mutation can be inherited to the children-and if it's +, screening mammogram & MRI should be done earlier & prophylactic surgery'll be recommended. Read more...

Breast cancer is genetic and not hereditary, is that correct?

Basic biology. It's easy to misunderstand. Genetic disease is usually hereditary -- only a few diseases of genes can't be inherited or passed on; new mutations are genetic but not hereditary. Inherited disease is almost always genetic. A variety of genes may be passed parent-to-child, each defining a "cancer family syndrome" but most cancer is sporadic. Read more...

I need to know what is the genetic connection for breast cancer?

There can be. Heredity plays a role in about 5% to 10% of patients with breast cancer. This is a good basic article: http://www.Cancer.Org/cancer/breastcancer/detailedguide/breast-cancer-risk-factors. Read more...