4 doctors weighed in:

Is letrozole different from tamoxifen?

4 doctors weighed in
Dr. Eric Brown
Breast Surgery
1 doctor agrees

In brief: Yes

Same general effect - decreases effects of estrogen and improves outcome in er + breast cancer.
Mechanism of action (how it works) is different. Letrozole cannot be used in premenopausal women.

In brief: Yes

Same general effect - decreases effects of estrogen and improves outcome in er + breast cancer.
Mechanism of action (how it works) is different. Letrozole cannot be used in premenopausal women.
Dr. Eric Brown
Dr. Eric Brown
Thank
Dr. Barry Rosen
Surgery
1 doctor agrees

In brief: Yes.

Tamoxifen is a selective estrogen receptor modulator; Letrozole is an aromatase inhibitor. Both drugs are used to treat hormone-positive breast cancer patients.
However, Letrozole can only be used after menopause. Furthermore, tamoxifen can also be used to prevent breast cancer in high-risk women.

In brief: Yes.

Tamoxifen is a selective estrogen receptor modulator; Letrozole is an aromatase inhibitor. Both drugs are used to treat hormone-positive breast cancer patients.
However, Letrozole can only be used after menopause. Furthermore, tamoxifen can also be used to prevent breast cancer in high-risk women.
Dr. Barry Rosen
Dr. Barry Rosen
Thank
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