How does dcis turn into stage 4 breast cancer?

Long process. While not all dcis will become invasive cancer, many cases will and to date we can not differentiate between those that will and those that won't. Those cases that become invasive, can then spread to lymph nodes or other organs. The latter, breast cancer that spreads to other organs, is stage IV breast cancer.
Pre-malignant . Dcis is a pre-malignant condition. Meaning the cells have the potential to become cancer if left in the breast, but at their current state they are not invasive. Dcis can turn into stage 4 breast cancer if they progress to invasive cancer.
Unknown. By definition, dcis is cancer confined to the breast ducts, without the ability to spread outside the breast. Nevertheless, rarely, a women with a history of previously-treated dcis will develop metastasis. A possible explanation is that a small invasive cancer was present but missed at the initial diagnosis. More likely, is that we just don't understand everything about dcis yet.

Related Questions

Can dcis breast cancer be caused by stress?

Unknown. It is very difficult if not impossible to attribute one factor alone as a cause of breast cancer. A recent study looked at stress levels in breast cancer patients and found the stress scores higher in those with more aggressive cancers, but it's hard to know whether the stress caused the aggressive form or if the aggressive cancer caused more stress. Regardless, stress, obviously, is never good. Read more...
Maybe. New research indicates that one form of hormone receptor negative breast cancer aka triple negative has found "stress" to be an independent risk factor for this type of breast cancer. This breast cancer is about 15% of all breast cancer. Little is known how to treat it and it has rather benign looking mammogram and ultrasound! dcis is not invasive--or really breast cancer--but can become ca. Read more...
Unclear. The data on this is unclear. Stress has a negative effect on many systems in the body. Read more...

What is the normal timescale in finding a breast cancer and being operated on? In relation to 5mm of intraductal carcinoma grade 3?

Varies. This can depend on your overall health, your surgical risks, timing of getting a surgeon consultation. Availability of the operating room, scheduling with radiology to localize such a small lesion of 5 mm. Etc. This may take 1-3 weeks to schedule depending on these and other potential factors. Read more...
6-8 wks. Intraductal cancer is not invasive. Grade 3 is more aggressive. If diagnosed via core needle biopsy, important to know that there may be invasive cancer present. This type of cancer will likely evolve into invasive cancer over time. Take your time to make a well informed decision. Maybe get a second opinion. Nothing will change over that time frame, and you'll be happy w your decision. Read more...
Month. I tell my patients that once you decide to operate you should do it within one month time. Read more...

In light of the recent article in the ny times on breast cancer would you recommend surgery for a 90 year old woman recently diagnosed with dcis?

Not enough info. Disclaimer: I'm a geriatrician, not a (surgical) oncologist. However, as I work closely w/our elderly, I would heartily recommend reading its follow up (http://www.nytimes.com/2015/08/21/health/breast-cancer-treatment-and-dcis-readers-react.html) then discussing w/her FamilyDoc. Answer depends upon her healthcare goals, overall health, mental health (any dementia?), heart & lung health etc. Read more...
Not necessary unless. Unless there is a palpable lump, this area of the breast can be monitored by your doctor and surgery held back. , it is an option in the future but only if the lump is growing in size both from your own impression(breast self examination should be done once monthly) and get a mammogram once every 6 months. There is no rush for surgery. Read more...
Depends. Depends on how good she is at 90 yrs and the size, type of DCIS. "Good-risk" DCIS has small size, low aggressive, and good-looking under microscope. You can leave it alone without surgery. "High-risk" DCIS has large size, aggressive, or ugly-looking. So, surgery (wide excision) may be considered if she functions well. However, radiation or tamoxifen is neither needed nor helpful in elderly. Read more...

In light of the recent article in the ny times on breast cancer would you recommend surgery for a 90 year old woman recently diagnosed with DCIS?

Maybe. It depends on the size of the area with DCIS and the patient's overall health. If the area of DCIS is large and palpable then I am worried that the area may erode into skin. If patient healthy enough then I would remove a palpable mass, even DCIS. If the patient is frail and the DCIS is small, I would do nothing because at that age she is more likely to die from something other than cancer. Read more...
No, but give choice. The most extensive study of 100,000 pts with DCIS followed over 20 years, the risk of dying , about 3.3 percent was very low, between the group that had lumpectomies with or without radiation and the group that had mastectomies.That said, a young 90 year old,wishing 110 span(OK?), need to be given a choice,since aggressive DCIS upped risk to just 7.8% in 20 yrs,so some opt for no tx,but close ffup. Read more...

I was told my mom had dcis and it was negative. No chemo. Can you have triple negative breast cancer with dcis? Or is the negative something else?

Cancer. Ductal carcinoma insitu is cancer. This case was probably low grade and not aggressive and taken care of by the lumpecty that helped diagnose it so no further chemo or radiation is needed. I am surprised tamoxifen was not recommended . Are you sure you have all the details? Cancer is cancer! Read more...
Talk to the doctor. I suggest you to d/w her surgeon or oncologist. Yes, dcis can be found coincidentally along with a triple negative breast cancer . However in this case it most likely means - dcis with negative evidence of invasive carcinoma - and that is why no chemo is needed on this case. However, i advice you to discuss with the doctor for confirmation . Read more...
Perhaps. Today, it is recommended that dcis be tested for er and pr expression to see if hormonal therapy may be beneficial, so the negative might refer to that. "triple negative" refers to er, pr and her-2-neu expression, but her-2-neu is not typically measured on dcis outside of clinical trial. Be sure to clarify this with your surgeon or your oncologist. Read more...