9 doctors weighed in:
Does pr-negative breast cancer respond to tamoxifen?
9 doctors weighed in

Dr. Barry Rosen
Surgery
5 doctors agree
In brief: It depends.
Tamoxifen is used to treat hormone-sensitive breast cancer.
This is determined by checking for estrogen receptors (er) and Progesterone receptors (pr) on the cancer. If the cancer is er+ and pr- (or vice-versa), it should respond to tamoxifen. However, if the cancer is er- and pr-, tamoxifen is not effective.

In brief: It depends.
Tamoxifen is used to treat hormone-sensitive breast cancer.
This is determined by checking for estrogen receptors (er) and Progesterone receptors (pr) on the cancer. If the cancer is er+ and pr- (or vice-versa), it should respond to tamoxifen. However, if the cancer is er- and pr-, tamoxifen is not effective.
Dr. Barry Rosen
Dr. Barry Rosen
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1 comment
Dr. Devon Webster
ER+ PR- breast cancers are more aggressive than ER+ PR+ and may respond less well to tamoxifen
Dr. Liawaty Ho
Internal Medicine - Hematology & Oncology
2 doctors agree
In brief: Yes if ER+
If the breast cancer is er +, tamoxifen will work- however it will not work if the cancer is er-, pr-.

In brief: Yes if ER+
If the breast cancer is er +, tamoxifen will work- however it will not work if the cancer is er-, pr-.
Dr. Liawaty Ho
Dr. Liawaty Ho
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Dr. Travis Kidner
Surgery - Oncology
1 doctor agrees
In brief: ER?
Response to tamoxifen depends on the er (estrogen receptor) status.

In brief: ER?
Response to tamoxifen depends on the er (estrogen receptor) status.
Dr. Travis Kidner
Dr. Travis Kidner
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