Does hormone replacement therapy increase your chances for breast cancer expotentionally?

Not exponentially. Data from the whi (women's health initiative) study show that estrogen alone does not significantly increase the risk of breast cancer, especially if started within 5 years of menopause. However, estrogen + Progesterone (needed when women still have a uterus to prevent uterine cancer) increases the risk of breast cancer to about 2x the baseline risk. Progesterone appears to be the "bad guy".
No. But long-term exposure is probably assocaited with a greater risk of breast cancer. But the actual risk is hard to prove and is certainly not exponential. Still, best not to take ert for more than 5 years unless you are very sympomatic from menopausal symptoms.
Absolutely Not. The whi as now reviewed was a very poor study overall and likely answers few clinical questions. I agree with the former answer that the progestin component was implicated but would not implicate Progesterone specifically. It was provera, (medroxyprogesterone) a synthetic Progesterone used in the study. The study population does not represent the typical patient we see. You need a consultation with hormone dr.

Related Questions

Hormone replacement therapy. Estrogen alone increases risk of uterine cancer. Adding progesterone increases risk of breast cancer, but reduces risk of uterine cancer. What's the right balance?

Individual. Yes, estrogen alone does increase the risk of uterine cancer over time. And yes the whi showed that the combination of a certain synthetic estrogen and a certain synthetic progestin increased the risk of breast cancer. But most specialists do not use those older types of synthetic hormones and with newer medications the risks are lower and different. So a balance can be achieved. Read more...

How safe is hormone replacement therapy if family history breast cancer?

Short term safety. There is no apparent increased risk for short term use of hormone therapy, with or without a family history. For longer term use (greater than 4 years) it is not clear exactly how the different estrogen and Progesterone formulations and combinations affect risk. Read more...
Varies. If a first order relative (mother, sister, daughter) has bc i would take ert only briefly and then only for severe symptoms. Remember that we try to prevent breast cancer by prescribing tamoxifen - which blocks estrogen. Adding ert definitely increases risk, somewhat, so you have to balance risks/benefits. Some women are miserable without it - and a short course may be appropriate for them. Read more...

Does hormone replacement therapy for menopausal symptoms cause breast cancer?

It can. The cause of breast cancer is so complex and poorly understood that it's better to talk about "associations" rather than "causes". Studies have shown that women who have used hormone replacement have a slightly higher incidence of breast cancer as compared to women that have not. In general, if you can avoid it, it's better to, especially if you have other risk factors for breast cancer. Read more...
In short, no. There are three human esrogens: Estradiol (from the ovary), estriol (from the placenta in pregnancy) and estrone (from peripheral fat conversion). Estrone is probably the culprit since women with excess peripheral body fat have increase rates of estrogen related cancers (breast, uterus, ovary, colon). Many oral estrogen hormones on the market are converted to estrone in the liver. Read more...
Increases risk. Hormone replacement therapy (hrt) has been shown to increase one's risk for breast cancer if taken for longer than 5 years. The current recommendation is to take low doses for a limited amount of time and then stop. There are some other non hormonal medications that can be used to help manage menopausal symptoms. Read more...
Depends. Virtually all of the studies showing that hrt increases breast cancer have been done on premarin (conjugated estrogens). Premarin (conjugated estrogens) is converted to estrone in the liver when taken orally. Overweight women convert adrenal hormones into estrone in peripheral body fat & have increased rates of estrogen dependent cancers (breast, colon, uterine). I suspect the culprit is estrone, not estradiol/estriol, the other human estrogens. Read more...

, ovarion or breast cancer dies not run in my family. May I safely continue hormone replacement.

Yes. As a neurologist, I am bias towards HRT because of known risk of dementia. I am sure oncologist would beg to differ with me since they are biased towards their profession. Very little to suggest if any that if there is no familly history, that HRT puts you at risk for cancer. Read more...
Be careful. At your age, the risk with hormone therapy increases. You need to be careful. When treating with hormones, you want to use the smallest dose possible and treat for the shortest time possible. It is very important that you meet with your physician to discuss your risks and consider checking genetic studies, and hormone levels. Make sure you are screening for breast disease as well. Be careful! Read more...

Hello doctor, I am on a hormone replacement therapy for menopause. Could this cause some pain in breasts?

Yes. Occasional mild breast tenderness on post-menopausal hormone therapy is not uncommon.It may however indicate that your dosing is too high. There is variation in the metabolism of estrogen in different women. Alcohol consumption may slow the clearance of estrogen. Breast pain in general needs evaluation. You should schedule an appointment with the doctor that prescribed your estrogen. Read more...

What's my risk of heart disease after a hysterectomy? My doctor recommended a hysterectomy and hormone replacement therapy, but I've read it can increase my risk of heart disease. I already have some risk factors. Does a hysterectomy make my chances of de

Hello. . Hello. If you ovaries are not removed; it won't change your risk for heart disease. However if both your ovaries and uterus are removed (which it looks like is the case for you since your doctor is recommending hormone replacement therapy) that can increase risk. With a total hysterectomy your estogen levels will drop. Estrogen helps to protect against heart disease. You develop a "surgical menopause" and this can lead to increasing sustances in your blood that cause clotting as well as making your blood vessels more susceptible to plaques or clots forming. Read more...
Heart disease. The risk of heart disease increases after a hysterectomy due to the decline in estrogen that has protective actions toward heart disease. I would look into bio-identical hormone replacement. Read more...

How does hormone replacement therapy increase libido?

Testosterone. Therapy can increase libido a lot. Estrogen therapy may have slight effects. It can also improve vaginal lubrication making it more enjoyable, and improve your overall well-being, so it seems like your desire has increased. Read more...