How long after my baby is born should I wait to vaccinate?

Within 48 hours. The first vaccine should be given within 48 hours of birth. Then next vaccine is given at 1-2 months of age. Do not delay vaccines unless directed to do so for medical reasons by your baby's doctor. Vaccines are important to the health of all children as they help to prevent many life threatening diseases .
Vaccinations. Babies in the usa receive the hepb vaccine 24-48 hours after delivery and then their infant vaccination series begin at 2 months of age.