Bad and good. Ldl is the low density lipoprotein cholesterol, commonly known as the "bad" cholesterol as it is the one that increases ones risk for heart disease (through depositing plaque to the arteries.) HDL is the high density lipoprotein cholesterol, commonly known as the "good" cholesterol as it has cardio-protective effects when elevated.
Lipoproteins. Cholesterol and triglycerides are fats transported in the blood inside carrier vehicles called lipoprotein particles. Following entry into the artery wall low density lipoprotein (ldl) particles directly promote development of atherosclerosis ("hardening of the arteries") and increase risk for heart attack and stroke. High density lipoprotein (HDL) particles work in several ways to decrease ather.
Pacman. Did you ever play pacman? Hdl is the LDL eating pacman. It helps decrease the total circulating LDL molecules and deliver them to the liver for storage and or disposal. You can not form plaques without inflammation of blood vessel walls and ldl (among other things). So the lower the circulating LDL levels are, the longer it takes to develop blocked arteries.
Nothing - Opposites. Lipoproteins are complex particles which carry fat molecules in the water outside cells. Generally, LDL particles deliver fat molecules into cells; HDL particles can remove fat molecules from cells. Too many LDL particles entering artery walls create problems & wbcs attempt to remove them. Without functioning HDL to remove fat from the wbcs, the wbcs die & this is called atherosclerotic plaque.
Influences Risk. Hdl does not directly affect the production or clearance of ldl, although both lipoproteins are important in understanding risk for heart attack and stroke. Cardiovascular (cvd) risk is related to the number of LDL particles (ldl-p) and the number of HDL particles (hdl-p). Lowering high ldl-p is the primary goal of therapy. When ldl-p is at goal, cvd risk is still high with low hdl-p.
LDL 100, HDL 40. The target LDL for preventing coronary heart disease is less than 100. The target HDL is greater than 40.
Low LDL, high HDL. Lowest LDL ('lousy') cholesterol and highest HDL ('healthy') cholesterol are the best to have. A LDL as low as 60-70 mg/dl and a HDL higher than 50-60 mg/dl are ideal.
Lousy vs healthy. Ldl (low denity lipoprotein) is bad (lousy) cholesterol and deposits in the wall of the arteries and triggers inflammation and atherosclerosis. It is thus a risk factor for heart disease and stroke. Hdl (high density lipoprotein) is healthy and is responsible for removing cholesterol from the wall of the arteries and carries it to theliver. It can thus reduce atherosclerosis and is protective.
Deliver - Remove. Ldl particles, within the water outside cells, deliver fat molecules to cells around the body. Hdl particles, also within the water outside cells, pickup fat molecules from cells which need to get rid of fat molecules. Other than very low numbers of large LDL particles drive atherosclerosis; HDL particles, if they are picking up & removing excess fat, help regress & prevent atherosclerotic plaque.
Cardiovascular Risk. Cholesterol is transported in the blood inside carrier vehicles called lipoprotein particles. Following entry into the artery wall low density lipoprotein (ldl) particles directly promote development of atherosclerosis ("hardening of the arteries") and increase risk for heart attack and stroke. High density lipoprotein (HDL) particles work in several ways to decrease atherosclerosis.
Cholesterol types. High density lipoprotein (hdl) is also refered to as " good cholesterol" represents the cholesterol being carried away from the cells (in the garbege trucks), therefore the higher the better. Low density lipoprotein (ldl) or "bad cholsterol" is in the delivery trucks, therefore the less the better.
Lipoproteins. High density lipoprotein (HDL) and low density lipoprotein (ldl) are particles that carry cholesterol in the blood. The number of LDL and HDL particles in blood are the best measures of LDL and HDL quantity. Cholesterol carried in these particles (ldl-c and hdl-c) provide a general, but often inaccurate, estimate of LDL and HDL levels.
Diet, exercise, meds. Hdl can improve through regular aerobic exercise. It also responds to nicotinic acid (niacin), as well as to statins, fibrtes, and fish oil. Ldl improves through weight loss, dietary modifications (less fat containing foods), and meds (statins, niacin, bile acid resins, and enteric binders like welchol (colesevelam) and zetia). Every pound lost in someone overweight typically drops LDL by 1-1.5 points.
Foods Meds Exercise. Hdl & LDL are complex protein particles which transport all fat molecules in the water outside cells. Get NMR particle test for accurate data. Carbs (sugar) & obesity raise LDL & especially ↓ large HDL levels. Thus go hf/lc foods. Statins & chol absorption inhibitors tend to ↓ LDL particle concentrations. Cutting carbs, Niacin & intense exercise usually ↑ hdl, esp large-hdl particle concentrations.
Lipids. Low fat and low carbohydate diet with lots of aerobic exercise.
HF/LC ↓BodyFat &Meds. Low fat theory by ancel keys; long promoted; opposite evidence. ↓ & efficient body fat is healthy. Ldl & HDL are complex particles, 80-100 proteins/particle: transport all fat molecules in h20 outside cells. Each LDL particle carries thousands of cholesterol, triglyceride, phospholipid & other fat molecules. Cholesterol often misleading, get NMR particle test. Statins↓ldl niacin↑hdl, carbs↑ldl↓hdl.
Hdl/ldl. Its better to have a high HDL with a high LDL but we can't say that a high HDL outweighs a high ldl, it still pays to lower the ldl.
Various ways. There are several ways to improve your lipid profile. Lowering LDL can be accomplished by dietary changes. There are also several plant/yeast derived natural products that also help reduce ldl. Medicines such as statins are potent at reducing LDL and some can raise hdl. Exercise both lowers LDL and raises hdl. If you smoke, stopping smoking also can lower LDL and raise hdl.
Diet & exercise. Moderate exercise (about 30 minutes 5 times a week) reduces LDL cholesterol and raises HDL cholesterol. Smoking can lower HDL levels, so stop smoking if you do. Eat lots of fruits, vegetables, whole grains and lean sources of protein. Include monounsaturated fats in your diet- olive oil/canola oil. Moderate consumption of alcohol may also positively impact HDL levels. 1 glass of wine a day.
Focus on one first. Bringing down LDL is more important and focus on correcting this first and HDL later - LDL can be corrected by vitamin E and correcting thyroid functions. Once this is corrected use carnitine to bring HDL up.