How should you make a cold sore stop hurting?

Options. Your doctor can prescribe valtrex (valacyclovir). Melissa officinalis or lemon balm (cream) has been shown in european studies to help expedite healing of cold sores. It can reduce healing time by half. Studies also show that regular use can help v recurrences. Brief supplementation w lysine 1, 000mg orally 3x a day at the onset, can also hasten healing. Your dermatologist can also provide laser treatments.
Laser treatment. Use of lasers on the cold sore will usually stop the pain and heal the sore quicker. Topical anesthetic (anbesol) will relieve the pain in the interim.