9 doctors weighed in:

How is Parkinson's disease inherited?

9 doctors weighed in
Dr. Anthony Mosley
Neurology
6 doctors agree

In brief: Mostly not inherited

The vast majority of people with parkinson's seem to get it sporadically, that is without any clear inheritance from family.
That being said, we've found around 12 genetic variants that seem to greatly increase the risk of developing pd in some families. Some of them are recessive (rarely crops up), and some are dominant (50% chance of getting it from 1 affected parent).

In brief: Mostly not inherited

The vast majority of people with parkinson's seem to get it sporadically, that is without any clear inheritance from family.
That being said, we've found around 12 genetic variants that seem to greatly increase the risk of developing pd in some families. Some of them are recessive (rarely crops up), and some are dominant (50% chance of getting it from 1 affected parent).
Dr. Anthony Mosley
Dr. Anthony Mosley
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Dr. Soren Singel
Neurosurgery

In brief: It is not

Pd is not a hereditary disease in the mendelian sense.

In brief: It is not

Pd is not a hereditary disease in the mendelian sense.
Dr. Soren Singel
Dr. Soren Singel
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1 comment
Dr. Joseph Savitt
There are several known genes that can lead to Parkinson's. The most common is called LRRK2. Testing is available through commercial labs. We do not treat inherited PD any differently than the sporadic form, so most testing is done for research purposes. The majority of PD is not caused by a gene we can test for, but there is a growing consensus that PD had a sizable gene component.
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