2 doctors weighed in:

Can I take primidone while breastfeeding?

2 doctors weighed in
Dr. James Ferguson
Pediatrics

In brief: Yes

Caution should be taken if breastfeeding while on this med.
Both primadone and a metabolite Phenobarbital will pass to baby and can produce sedation in the neonatal period. Relative transfer <9% of mothers dose, with serum levels from trace to <1/2 therapuetic for both. Harriet lane c2-caution, hale L3 moderately safe. See medications and mothers milk 14ed. Hale, 2010.

In brief: Yes

Caution should be taken if breastfeeding while on this med.
Both primadone and a metabolite Phenobarbital will pass to baby and can produce sedation in the neonatal period. Relative transfer <9% of mothers dose, with serum levels from trace to <1/2 therapuetic for both. Harriet lane c2-caution, hale L3 moderately safe. See medications and mothers milk 14ed. Hale, 2010.
Dr. James Ferguson
Dr. James Ferguson
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Dr. Irwin Berkowitz
Pediatrics

In brief: No

Primidone has been found to cause malformations in the fetus.
The situation must be evaluated on a case to case basis as the health of the mother is of paramount importance.

In brief: No

Primidone has been found to cause malformations in the fetus.
The situation must be evaluated on a case to case basis as the health of the mother is of paramount importance.
Dr. Irwin Berkowitz
Dr. Irwin Berkowitz
Thank
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