2 doctors weighed in:

Are obese people resistant to leptin?

2 doctors weighed in
Dr. Vasu Brown
Wound care
1 doctor agrees

In brief: Yes

Although leptin is a circulating signal that reduces appetite, obese individuals generally exhibit an unusually high circulating concentration of leptin.
These people are said to be resistant to the effects of leptin, in much the same way that people with type 2 diabetes are resistant to the effects of insulin.

In brief: Yes

Although leptin is a circulating signal that reduces appetite, obese individuals generally exhibit an unusually high circulating concentration of leptin.
These people are said to be resistant to the effects of leptin, in much the same way that people with type 2 diabetes are resistant to the effects of insulin.
Dr. Vasu Brown
Dr. Vasu Brown
Thank
3 comments
Dr. Vasu Brown
We use in our practice L-Glutamine 1000mg at night and 500mg whenever people feel like munching
Dr. Vasu Brown
the reason is food allergy causes the inflammatory response in body and creates pancreas insulinweep
Dr. Michael Rothman
Internal Medicine

In brief: Yes

Leptin resistance can result from excessive stress.
This stress can be immune system stress, hormonal stress or nervous system stress. The excess stress produces chemicals called "cytokines" which then injure your hypothalamus and impair the hypothalamic response to leptin. Hence the leptin resistance. This explains why so many obese people have trouble losing weight even if they do not eat much.

In brief: Yes

Leptin resistance can result from excessive stress.
This stress can be immune system stress, hormonal stress or nervous system stress. The excess stress produces chemicals called "cytokines" which then injure your hypothalamus and impair the hypothalamic response to leptin. Hence the leptin resistance. This explains why so many obese people have trouble losing weight even if they do not eat much.
Dr. Michael Rothman
Dr. Michael Rothman
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