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What are the differences between grehlin and leptin?

2 doctors weighed in
Dr. J Roberts
Surgery - Vascular

In brief: The yin/yang of diet

Gherlin, a peptide secreted by the fundus of the stomach, increases before meals and falls after meals; whereas leptin, produced by adipose cells, interacts with the cns, specifically neuropeptide y in the arcuate nucleus wherein it induces satiety, or a sense of fullness.
Currently, intense research exists to temper obesity via a pill and diet, rather than, say, gastric bypass.

In brief: The yin/yang of diet

Gherlin, a peptide secreted by the fundus of the stomach, increases before meals and falls after meals; whereas leptin, produced by adipose cells, interacts with the cns, specifically neuropeptide y in the arcuate nucleus wherein it induces satiety, or a sense of fullness.
Currently, intense research exists to temper obesity via a pill and diet, rather than, say, gastric bypass.
Dr. J Roberts
Dr. J Roberts
Thank
Dr. Vasu Brown
Wound care

In brief: Satiation vs hunger

Leptin is for satiation vs ghrelin for hunger. Leptin is a mediator of long-term regulation of energy balance, suppressing food intake and thereby inducing weight loss.
Ghrelin on the other hand is a fast-acting hormone, seemingly playing a role in meal initiation.

In brief: Satiation vs hunger

Leptin is for satiation vs ghrelin for hunger. Leptin is a mediator of long-term regulation of energy balance, suppressing food intake and thereby inducing weight loss.
Ghrelin on the other hand is a fast-acting hormone, seemingly playing a role in meal initiation.
Dr. Vasu Brown
Dr. Vasu Brown
Thank
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