7% familial incidence of hypospadias
. Approx. 10% of brothers with hypospadias will also have the same condition. I have seen between 1500 - 2000 boys with hypospadias & only a handful had fathers who also have hypospadias. Threre have about 3 families where there were 3 or 4 generations with hypospadias. Inheritance is felt to be polygenic & not due to a single gene.