3 doctors weighed in:

Is hirschsprung's disease inheritiable?

3 doctors weighed in
Dr. Troy Reyna
Surgery - Pediatric
1 doctor agrees

In brief: Constipation

Hirschsprung's disease is a congenital disease.
You are born with it. It causes constipation and /or obstruction due to non functioning of intestinal nerves. It is treatable, but may require surgery to diagnose and treat. In some cases it is heriditary but usually it is sporadic.

In brief: Constipation

Hirschsprung's disease is a congenital disease.
You are born with it. It causes constipation and /or obstruction due to non functioning of intestinal nerves. It is treatable, but may require surgery to diagnose and treat. In some cases it is heriditary but usually it is sporadic.
Dr. Troy Reyna
Dr. Troy Reyna
Thank
Dr. Gerald Mandell
Nuclear Medicine

In brief: Some familial cases

Disease can be familial or develop spontaneously.
It is more common in boys than girlls.Approximately 3-5 % of male siblings and 1 percent of female siblings of children with short-segment disease also have the disease.Risk substantially higher (12.4-33%) in siblings of children with total colonic involvement.Eight genomes have been associated with Hirschsprung’s disease.Most cases not familial.

In brief: Some familial cases

Disease can be familial or develop spontaneously.
It is more common in boys than girlls.Approximately 3-5 % of male siblings and 1 percent of female siblings of children with short-segment disease also have the disease.Risk substantially higher (12.4-33%) in siblings of children with total colonic involvement.Eight genomes have been associated with Hirschsprung’s disease.Most cases not familial.
Dr. Gerald Mandell
Dr. Gerald Mandell
Thank