What is the difference between progressive supranuclear palsy (psp) and Parkinson's disease?

Parkinson's Disease. Progressive supracuclear palsy is a severe form of parkinsonism. It is characterized by no or minimal response to levodopa, prominent subcortical cognitive impairment, severe balance disorder, axial dystonias, and the classical inability to voluntarily move eyes in vertical plane. In contrast, idiopathic parkinson's disease commonly has better response to levodopa, resting tremors, slower decline.
Difft diseases. Psp usually limited to eye movement. Pd affects extremities.
Overlap. Both are degenerative brain disorder. In psp there are eye movement disorder along with some parkinonian features. Also course of the disease is different.

Related Questions

Is progressive supranuclear palsy a demyelinating disease?

PSP. Progressive supranuclear palsy: the disorder's long name indicates that the disease begins slowly and continues to get worse (progressive), and causes weakness (palsy) by damaging certain parts of the brain above pea-sized structures called nuclei that control eye movements (supranuclear). It is central; demyelinating conditions occur in the peripheral nervous system.
No, tau protein. No, tau protein deposits & neurofibrillary tangles in neurons cause the death of these cells. Because they are in some similar areas as parkinson's disease, psp can appear similar clinically, but there are clear differences. Treatment approaches are roughly the same with different areas needing most attention. Primarily balance/falls/injury, did inhibiting dementia & dysphagia/aspiration.

Which disease is similar to progressive supranuclear palsy?

Dementia. Progressive supranuclear palsy is a degeneration of brain cells that leads to difficulty walking, short-term memory loss and an inability to look up. It can be confused with alzheimer's disease or parkinson's disease.

Can you suggest any alternative treaments for progressive supranuclear palsy (psp) like ayurveda, homeopathy or siddha?

Stem cells. This is a neurologic condition which has no real cure. I currently am implanting stem cells for patients with this condition, into the CSF. These are autologous cells from your own fat. IRB-approved patient-funded study. Contact 949-642-6787 for more details. Make sure you have a second opinion on the diagnosis.

What are some alternate treaments for progressive supranuclear palsy (psp) like ayurveda, homeopathy or siddha?

PSP. With any of these other forms of medicine, you would need very skilled, experienced professionals to work with you alongside your conventional neurologist. Many conventional physicians are becoming trained in Ayurveda and homeopathy -- I'm sorry, but I know little about siddha although this one originated in india like ayurveda. For homeopathic physicians, you can see: http://tinyurl. Com/lgsovco.

What are some alternative treatments for progressive supranuclear palsy (psp) like ayurveda, homeopathy or siddha?

Collaborative care. Psp is a rare degenerative disease of the brain involving movement & balance as well as changes in mood, behavior and personality. Conventional medicine has no cure. Homeopathy does not treat the specific pathological condition, but can help the person by applying the single homeopathic medicine called for by his/her specific experience. You need a very well-trained homeopath to work with you.

Could anesthesia cause progressive supranuclear palsy (psp)?

PSP. There is zero evidence linking PSP to any form of anesthesia. Having said that it is also true that the cause (s) of PSP are unknown. Its virtually unheard of in people under 40. It is known that an abnormal protein (tau) builds up like some other neuro degenerative diseases. If you have PSP, you would be more at risk for other complications of anesthesia.
Not likely. No one knows for sure what causes it. It is a degenerative neurologic disease a little similar to Parkinson's disease in a comparable area of the brain. The cause may be genetic, viral, though no one really knows. It is very very rare.

Is it possible for anesthesia cause progressive supranuclear palsy (psp)?

NO. Psp was described by steele and richardson many years ago. It was then found to be a progressive disease similar to parkinsons. It is assumed that it is a form of slow virus, but no definite or consistent cause has been uncovered. Certain stress states may bring out the symptoms, including surgery and anesthesia, but can not be considered as the cause.
Unlikely. Though anesthetics do have an effect on the brain, it is unlikely that they would cause this problem. The anesthetics that we use can decrease blood flow to certain areas of the brain, so they might unmask a pre-existing psp, but again that is speculation. I would talk to your neurologist about this problem.

How is progressive supranuclear palsy (psp) diagnosed?

Cannot look up. Similar to but worse prognosis than Parkinson's disease sharing the rigidity and poverty of movements, inability to look up with head kept straight.
Exam. Inability to move the eyes voluntarily, but they can move when the head is jerked left and right.
Psp. The diagnosis of psp is confirmed by clinical exam including a neurological and eye exam.

I was diagnosed with progressive supranuclear palsy 5 years ago. Are there any good clinical trials available for psp?

Try this. Psp is frustrating and unfortnately progressive. Also, there just aren't many doctors with a ton of experience with this "rare" condition. See: http://www. Pspinformation. Com/ you may be able to find what you are looking for, or at least get connected to a support network.