What is the definition of hereditary spastic paraplegia?

Genetic? Hereditary spastic pareplegia is the name given to a mainly motor disability often in lower extremities slowly progressive with a geographical distribution.The condition often does not cause sensory or bladder problems and all tests including mri, CSF studies B12 levels etc are normal some of these cases have antibodies to htlv 1 viruses in the blood or cerebrospinal fluid.
Genetic disorder. This is a slowly progressive usually autosomal dominant (70%) disorder causing progressive weakness and spasticity (tightness and spasms) in the legs. While there is no specific cure, meds can alleviate symptoms, and physical and occupational therapies may help.

Related Questions

What is the definition of spastic paraplegia?

SPASTIC DIPLEGIA. Spastic paraplegia means weakness in all four limbs, but legs are weaker than the arms, spasticity will be more obvious in legs rather than arms, spastic paraplegia or also called diplegia is common in premature babies who have complication of prematurity like intraventricular hemmorhage which leads to white matter changes around the midline in the brain which controls the motor function of the le. Read more...
Paralysis. Paraplegia means bilateral leg paralysis, and spasticity is a knife clasp catching due to increased tone in the paralyzed legs. This can be very painful and challenging to control, and is far worse if due to spinal cord issues. Read more...

What is spastic paraplegia?

See below. Paraplegia refers to weakness or paralysis of the lower extremities. Spastic refers to the tone of the muscle which is abnormally increased. Spastic paraplegia occurs when there is damage to either the spinal cord, brain or both. There are many causes including trauma, infections, vascular problems, and toxins. Read more...

What can you tell me about spastic paraplegia? How dangerous is it?

If your question is . about an Hereditary Spastic Paraplegia, please specify age of onset of symptoms, clinical course thus far & results of genetic testing. Progression of symptoms depends on the type, as you can see on this site: http://www.ncbi.nlm.nih.gov/books/NBK1509/. It has medical terminology, but you can get an idea of the different types & different patterns of inheritance. Read more...

Paraparisis cause? Its also known as familiar spastic paraplegia?

See below. Paraparesis is a milder form of paraplegia ( which should mean no movement in the lower extremities but is sometimes used synonymously) familial spastic paraplegia is a paraplegia with family history of unknown etiology and is diagnosed when all the other causes have been ruled out. Read more...

My brother is 29 & he had spastic paraplegia since 9 yrs. Now he taking leofen 10mg also doing physiotherapy every day. Is there a complete cure.

No. Do you mean hereditary spastic paraplegia? He has NOT had it since he was 9. He's had it since the moment he was conceived. That's what hereditary means. It didn't start at 9, it only became apparent then. There is no way his doctors could not have told you long ago that there is no cure. A cure would mean altering his genes, which is still in the realm of acience fiction. Read more...