What is the definition of hereditary spastic paraparesis?

Hereditary SP. Hsp, is a genetic disorder transmitted as autosomal dominant, meaning one of the parent has the disease in order to pass it to the offspring. It is a progressive spasticity in the legs , may be associated with hypertonic urinary incontinence, seizure, dementia, or peripheral neuropathy.
Read on. A condition usually causing slowly progressive mainly motor weakness specially in the lower extremities it sometimes is familial, although the cause may be sharing the same environment. A connection between this condition and an htlv1 virus infection is suggested as a cause.

Related Questions

What is hereditary spastic paraparesis?

Rare condition. Progressive leg weakness and spasticity (tightness and catching of leg with flexion), caused by autosomal dominant and recessive or x-linked genetics, with usual slow progression and normal life span. Mri may demonstrate atrophy of brain and/or spinal cord. Read more...

What can I do about my hereditary spastic paraparesis?

Treat the symptoms. If the process is stable, and not progressing, best to try anti-spasticity meds, such as baclofen, tizanidine, or even a pump. Botox injections, although off-label, might be useful. Acupuncture has promise. Splints, braces, exercises all may help. If legal in your state, medical marijuana may help, as the research from europe suggests benefit in the spasticity associated with ms. Read more...

Any treatment for heriditary spastic paraparesis? Accompanied by sensory neuropathy?

Symptomatic treatmen. Hsp is a group of inherited disorders, often insidiously progressive and severe. There are no effective treatments to the underlying damage to the nerve axons so treatment is symptomatic. Baclofen, dantrolene and tinazidine may help with spasticity; oxybutinin with urinary urgency; gabapentin, Pregabalin and duloxetine for neuropathy. Vitamins, d, e and b6 may also help. Physical therapy also. Read more...

What is tropical spastic paraparesis?

Disorder of sp cord. A subacute condition with impairment of lower extremity >upper extremity function, sensory abnormalities, bladder functioning and girdling lumbar pain. About 80 % of patients with tsp have antibodies to htlv-1 (not aids virus..Htlv-3) the disorder and similar disorders were described in caribbean patients. Read more...