Hard to say
First thing is to exclude things that cause rls, like many medications (antihistamines and some antidepressants
and major tranquillizers) and iron
There are many naturopathic and homeopathic remedies (restful legs powder, restedlegs), but there are no studies that really prove their worth. Some people benefit from trigger point therapy. See a naturopathic or homeopathic doctor for help.