7 doctors weighed in:

Is reperfusion injury?

7 doctors weighed in
Dr. Vasu Brown
Wound care
6 doctors agree

In brief: Reperfusion injury

Reperfusion injury refers to tissue damage caused when blood supply returns to the tissue after a period of ischemia or lack of oxygen.
The absence of oxygen and nutrients from blood during the ischemic period creates a condition in which the restoration of circulation results in leaking from blood vessel the substances that produce damage to tissue - the degraded enzymes create further damage.

In brief: Reperfusion injury

Reperfusion injury refers to tissue damage caused when blood supply returns to the tissue after a period of ischemia or lack of oxygen.
The absence of oxygen and nutrients from blood during the ischemic period creates a condition in which the restoration of circulation results in leaking from blood vessel the substances that produce damage to tissue - the degraded enzymes create further damage.
Dr. Vasu Brown
Dr. Vasu Brown
Thank
Dr. Joseph Sucher
Surgery - Trauma

In brief: Great Question!

Reperfusion injury is something that occurs when an organ or extremity is denied blood flow (perfusion) and subsequently blood flow is restored.
At this point, without very specific therapy and monitoring, reperfusion injury can ensue. The cytotoxins are released at this point, with resultant cellular injury and apoptosis occurring. This can lead to limb or organ damage/loss.

In brief: Great Question!

Reperfusion injury is something that occurs when an organ or extremity is denied blood flow (perfusion) and subsequently blood flow is restored.
At this point, without very specific therapy and monitoring, reperfusion injury can ensue. The cytotoxins are released at this point, with resultant cellular injury and apoptosis occurring. This can lead to limb or organ damage/loss.
Dr. Joseph Sucher
Dr. Joseph Sucher
Thank
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