What is a prion disease?

Prions. Prions are a protein that is misfolded and accumulates and deposits in the body.
Infectious protein. Infection from an infectious protein particle. Conditions include kuru, mad cow, creutzfeld jakob etc.

Related Questions

What are the symptoms of a prion disease?

No definite. Prion disease is suspected when pt. Shows rapidly progressive dementia like features, including seizure. Symptoms of dementia are many many. Read more...
Neuro. Decline in mental function, rapid over a few months. The hallmark symptom, often present, is myoclonic jerks while fully conscious. Lack of coordination is common if the cerebellum is involved. Read more...

What are the symptoms of a prion disease? Prion disease?

Multiple diseases. Prion diseases included a number of disorders. The most prominent, cjd, causes, dementia, ataxia, weird painful sensations, seizures, wasting etc. For more information please consult the following site. http://www.cdc.gov/ncidod/dvrd/prions/. Read more...

Describe prion diseases?

Rare diseases. Prion diseases are rare disorders that the effected and transmitted by misfolded proteins. Read the site below for more information. http://ghr.nlm.nih.gov/condition/prion-disease. Read more...
Prion disease. Fatal Familial Insomnia, CJD, Varient CJD, Scrapie, KURU all have in common the relentless progression caused by infection with something that is less sophisticated than a virus. Most are acquired from ingestion of contaminated brains (or meat in the case of Varient CJD) CJD can be contracted through corneal transplant or transfusion of contaminated blood or blood products. . Read more...

How can prion diseases be prevented?

Not much. There's not much we can do at present as some forms of prion diseases have to do with genetic mutations. Prion diseases can be transmitted by exposure to prion-contaminated tissues during a medical procedure. Another type of prion disease in humans, vcjd, is acquired by eating beef products obtained from cattle with prion disease. So stay away from beef from places with endemic prion disease. Read more...
Little. Prions are infectious only in great concentration. Concentration occurs when there is a cycle of of infection-->ingestion-->infection-->...As with kuru when peopl eat the brains of infected ancestors, become infected and are then ingested. The same can happen with mad cow disease when infected cattle are themselves fed to cattle. So, avoid beef fed on cattle parts. Read more...
There are many forms. of Prion disease from Fatal Familial Insomnia to Kuru. Generally speaking I would avoid eating brains form any source (see my editorial in the British Medical Journal Lancet ) also avoid blood products from potentially contaminated sources where there have been cases of Variant CJD (Mad cow disease). Some cases occur through spontaneous mutations, corneal transplants and contaminated allographs. Read more...

What is the most common way a person gets a prion disease?

Sporadic. Most cases of cjd are sporadic without a known inciting factor. For more info see the site below: http://www.Cdc.Gov/ncidod/dvrd/prions/. Read more...
Ingestion. Current research suggests that the primary method of infection in animals is through ingestion. Knowledge in this field is in the formative stages, and research is continuing, trying to elucidate the means of transmission. Good news: clearly, occurrence is not common in humans; and when it occurs in animals, e.g. "mad cow disease", is isolated and eliminated, thus no spread. Read more...

Why do prion diseases have such long incubation periods? Can they be stopped at all?

Supportive care only. The duration of incubation of prions is probably related to the folding state of the inoculum and the sequence of the host prion protein. At present, there is no effective treatment for prion diseases, and all are universally fatal. Read more...

How do I make sure I never get a prion disease? Saw something about it on tv and they look horrifying

Don't think about it. Prion disease is extremely rare. Classic cases are usually genetic or having to do with cannibalism. Mad cow disease causing human prion disease is a possibility but it is not well established. One can eliminate meat from diet but there is no way to ensure you won't get it. It is out of your control so relax and don't let something like this stop you from living. Read more...

Are prion diseases more common among people who hunt and eat what they kill? (Due to the meat not being tested for disease)

Dept of Health. Contact your local Department of Health and ask if prion disease is a problem in your region. It is unlikely it would be infecting your venison. Read more...

Have we gotten ahead of the game on prion diseases? Or are prion diseases likely to be major social/public health problems down the road?

Hard to say. The mad cow epidemic and subsequent outbreak of vcjd was brought to the surface by feeding animal proteins to herbavores. Science has quite a lot more to learn about prions. They are likely to be involved in other processes and not all related to disease states. Read more...