12 doctors weighed in:
Why does vascular disease develop in diabetics?
12 doctors weighed in

Dr. Susan Wingo
Internal Medicine - Endocrinology
4 doctors agree
In brief: Inflammation
Diabetes can lead to protein changes and inflammation, leading to atherosclerosis, or narrowing and stiffening of blood vessels.
Depending on the location, these narrowed arteries may cause heart attack (heart or coronary arteries), stroke (carotid), amputations due to infection/poor healing (legs & feet), blindness (eyes), and kidney failure (kidneys).

In brief: Inflammation
Diabetes can lead to protein changes and inflammation, leading to atherosclerosis, or narrowing and stiffening of blood vessels.
Depending on the location, these narrowed arteries may cause heart attack (heart or coronary arteries), stroke (carotid), amputations due to infection/poor healing (legs & feet), blindness (eyes), and kidney failure (kidneys).
Dr. Susan Wingo
Dr. Susan Wingo
Thank
Dr. Steven Ajluni
Internal Medicine - Cardiology
4 doctors agree
In brief: Inflammatory changes
Diabetes and the Insulin resistant state yields increased endothelial dysfunction and helps accelerate the cascade of inflammation that leads to atherosclerosis and vascular narrowing.
This exacerbates also the risk of plaque rupture that can lead to acute coronary states. 80% of diabetics die ultimately of vascular causes (mi, cva, or complications of pvod).

In brief: Inflammatory changes
Diabetes and the Insulin resistant state yields increased endothelial dysfunction and helps accelerate the cascade of inflammation that leads to atherosclerosis and vascular narrowing.
This exacerbates also the risk of plaque rupture that can lead to acute coronary states. 80% of diabetics die ultimately of vascular causes (mi, cva, or complications of pvod).
Dr. Steven Ajluni
Dr. Steven Ajluni
Thank
Dr. Rick Koch
Internal Medicine - Cardiology
2 doctors agree
In brief: High glucose blood
Levels over time promotes inflammation and atherosclerosis formation.

In brief: High glucose blood
Levels over time promotes inflammation and atherosclerosis formation.
Dr. Rick Koch
Dr. Rick Koch
Thank
Dr. PHILLIP KIM
Family Medicine
2 doctors agree
In brief: Inflammation
Uncontrolled blood glucose due to diabetes leads to chronic inflammation in the vasculature.
This leads to damage and poor repair response.

In brief: Inflammation
Uncontrolled blood glucose due to diabetes leads to chronic inflammation in the vasculature.
This leads to damage and poor repair response.
Dr. PHILLIP KIM
Dr. PHILLIP KIM
Thank
Get help from a real doctor now
Dr. Bennett Machanic
Board Certified, Neurology
48 years in practice
55M people helped
Continue
108,000 doctors available
Read more answers from doctors