Several. Neurofibromatosis type 1 (nf 1) is genetically determined and is the most common. 50% of cases are inherited but 50% arise from spontaneous mutation. Nf 2 is similar.
NF-1 AND 2. Neurofibromatosis, is a genetic disorder transmitted as autosomal dominant, meaning one of the parents needs to be affected to transmit the disease to 50% of the offsprings. Nf is considered as one of the neurocutaneous disorders affected the skin and the brain.