The two main medications used today to treat narcolepsy
include xyrem (sodium oxybate) which is very helpful for treating cataplexy
and excessive day time sleepiness
and nuvigil/provigil which is used to promote wakefullness.
The current "standard of care" is to give these medications together (xyrem at night and Nuvigil by day. Other medications are used but these are the current standard.