6 doctors weighed in:
How do antiepileptic medications work to control seizures?
6 doctors weighed in

Dr. William Goldie
Pediatrics - Neurology
2 doctors agree
In brief: Good question
They just do - sometimes.
We can sound erudite with eloquent explanations. But no one really knows. Many years ago one lab had huge success with many agents as long as they were suspended in a certain solvent. It turned out the solvent was valproic acid. When they realized it was the actual active agent, it was refined and marketed as depakote.

In brief: Good question
They just do - sometimes.
We can sound erudite with eloquent explanations. But no one really knows. Many years ago one lab had huge success with many agents as long as they were suspended in a certain solvent. It turned out the solvent was valproic acid. When they realized it was the actual active agent, it was refined and marketed as depakote.
Dr. William Goldie
Dr. William Goldie
Thank
2 doctors agree
In brief: Chemical way.
Anti epileptics work at molecular level by controlling ionic channel gate in cell membrane like na, k, ca, nmda.
Etc thereby altering excitability of cell membrane. It is a very advanced detailed science.

In brief: Chemical way.
Anti epileptics work at molecular level by controlling ionic channel gate in cell membrane like na, k, ca, nmda.
Etc thereby altering excitability of cell membrane. It is a very advanced detailed science.
Dr. Nalinaksha Joshi
Dr. Nalinaksha Joshi
Thank
1 comment
Dr. Mark Fisher
In some cases the mechanism of action (MOA) is clear; in others, several mechanisms may operate at once; in still others the MOA is conjectural or even unknown.
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