Positive & Negative. Ect is reserved for the most severe cases. ~ 60% will go into remission, ~20% will respond some, & ~20% will not improve. 50% will relapse in 6mos. Most common immediate side effect is headache. Memory impairment is the most serious side effect but is mitigated by electrode placement. Right unilateral (RUL) is as effective as traditional bilateral placement, but memory is much less affected.