10 doctors weighed in:
What parts of the brain are most likely affected by alzheimer's disease?
10 doctors weighed in

Dr. Kalyn Diamond
Clinical Psychology
6 doctors agree
In brief: Medial temporal lobe
Alzheimer's starts in the hippocampus and the medial temporal lobe.
In end-stage alzheimer’s there is widespread atrophy. Early onset alzheimer’s (<65 years old) has a different presentation. There is usually some mild hippocampal atrophy, but the most striking finding is parietal atrophy, with atrophy of the posterior cingulum and the precuneus. The hippocampus can be normal. Hope this helps.

In brief: Medial temporal lobe
Alzheimer's starts in the hippocampus and the medial temporal lobe.
In end-stage alzheimer’s there is widespread atrophy. Early onset alzheimer’s (<65 years old) has a different presentation. There is usually some mild hippocampal atrophy, but the most striking finding is parietal atrophy, with atrophy of the posterior cingulum and the precuneus. The hippocampus can be normal. Hope this helps.
Dr. Kalyn Diamond
Dr. Kalyn Diamond
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Dr. Felix Brizuela
Neurology
1 doctor agrees
In brief: Base, then the rest
Usually starts in the front, lower part of the brain called the nucleus basalis of meynert, but then to the rest of the brain as the disease progresses.

In brief: Base, then the rest
Usually starts in the front, lower part of the brain called the nucleus basalis of meynert, but then to the rest of the brain as the disease progresses.
Dr. Felix Brizuela
Dr. Felix Brizuela
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Dr. Maureen Nash
Psychiatry - Geriatric
In brief: Temporal lobes
Alzheimers is thought to start in the temporal lobes followed by the parietal lobes.
As the disease progresses the frontal lobes can also be affected. The brain stem is not affected.

In brief: Temporal lobes
Alzheimers is thought to start in the temporal lobes followed by the parietal lobes.
As the disease progresses the frontal lobes can also be affected. The brain stem is not affected.
Dr. Maureen Nash
Dr. Maureen Nash
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